GeCIP Governance, Oversight and Management
The GeCIP Board
The GeCIP Board oversees the Genomics England Clinical Interpretation Partnership and is chaired by Professor Dame Kay Davies, who also represents GeCIP on the Genomics England Board.
Each GeCIP funder is represented on the GeCIP Board which consists of: Dr David Cox (National Institute for Health Research/Department of Health), Dr Nathan Richardson (Medical Research Council), Dr Michael Dunn (the Wellcome Trust) and Dr Rowena Sharp (Cancer Research UK). Genomics England is represented by its Chief Scientist and Chief Technology Officer.
Members of the board include a GeCIP domain lead elected from within each of the cancer, rare diseases, and infectious diseases themes.
Up to three places are reserved for the representatives of the Participant Panel and they contribute and vote as any other member of the GeCIP Board. The individual Participant Panel representatives are free to rotate attendance at the GeCIP Board according to their availability.
The GeCIP Board was constituted on Friday 17 June 2015. Its main roles are:
- To oversee the clinical interpretation programme and act as a focus for coordination
- To sponsor a twice yearly conference of all active GeCIP members
- To receive advice from Genomics England Advisory Committees
- To provide advice to the Genomics England Board.
The role of the Office of the Genomics England Chief Scientist
GeCIP is operated by the Office of the Genomics England Chief Scientist, with the assistance of the steering committee. They oversee the following activities:
- Oversee GeCIP overall management and coordination
- Manage appointment process for GeCIP science domain members
- Support the work of the GeCIP science domains; facilitate meetings and knowledge sharing, provide administrative support
- Manage the interface with GeCIP funders
- Manage the interface with NHSE, clinical regulatory bodies, NICE and MHRA
- Manage the interface and relationship with the Royal Colleges
- Enable Health Education England and other funders’ training programmes
- Deliver informatics training and support
- Provide input to Genomics England data sharing agreements and contracts with users
- Deliver data embassy (access to anonymised data and Genomics England Knowledge Base for the disease area in question)
- Deliver operational governance oversight (provide assurance to the Genomics England Board on contractual obligations and data security and ethical governance compliance within the GeCIP environment and user community)
- Maintain the list of pathogenic variants that may be fed back to treating clinicians (incidental findings)
The GeCIP Steering Committee
The Office of the Genomics England Chief Scientist will convene a Steering Committee to input into the smooth running and transfer of knowledge across the GeCIP domains. The membership will consist of a representative from each domain and will be chaired by the Chief Scientist for Genomics England. The committee will include the Genomics England Chief Scientist’s team, representation from the Genomics England Informatics team, representation from the Ethics Advisory Committee, representatives of the public and patients. The GeCIP Steering Committee will directly report to the GeCIP Board.
The GeCIP members
All GeCIP researchers and clinicians will be expected to adopt the highest ethical standards with regard to research governance, data access and security in accordance with the terms of the Genomics England informed consent.