Genomics England successfully led the world-leading 100,000 Genomes Project, which compared and analysed individuals’ genetic codes to help diagnose, treat and prevent illness.

We're now accelerating our impact, working with the NHS to further develop and embed genomic healthcare and research in Britain. Our next chapter involves working with patients, doctors, scientists, government and industry to improve genomic testing, and help researchers access the health data and technology they need to make new medical discoveries and create more effective, targeted medicines for everybody.

Our team of Bioinformaticians provide high calibre bioinformatics research support to external researchers and industrial partners by enabling analysis, facilitating access to datasets and ensuring optimal use of the Genomics England Research Data Centre.

This Bioinformatician within Research Support will act as a second line of support for users of the Research Environment and take responsibility for delivering the best outcome for users. They will be intimately familiar with the data and applications.

The research support team is also responsible for the stewardship of genomic data and its effective flow through products into the various research products.

The role includes elements of a bioinformatician and data analyst, ensuring that our users have an excellent customer experience.

In this role, you'll be a superuser of our datasets and our research environment, advocating both internally and externally, while working with researchers from academia and industry to ensure their scientific projects are successful.

You will support our users in working with our data and contribute to data generation, intake and extraction through airlocks.

You will also develop templates and documentation on accessing data and running analyses in the environment, and carry out custom analyses on demand.

Other duties include:

• Extensive hands-on experience in analysis of large-scale genomic data using bioinformatics tools and pipelines.
• Competence in R, Python or similar language appropriate for large-scale genomics analysis.
• Experience with working in the cloud and familiarity with the services and benefits it brings.
• Demonstrable experience in using next generation sequencing data.

To be successful in this role you will have a background in human disease genetics, preferably in cancer or rare disease, demonstrated by publication record or industry track record.

Experience writing pipelines in WDL or Nextflow

Proven ability to communicate with stakeholders from diverse backgrounds (e.g. management, IT, R&D, biology, bioinformatics) and a clear understanding of clinical and phenotypic data management and the sensitivities surrounding patient cohort data which is highly advantageous.

You'll have excellent interpersonal skills, keeping track of customer relationships, providing high calibre troubleshooting, identifying unmet customer needs and suggesting solutions to improve material.

Educated to MSc level (or higher), in Bioinformatics, Biostatistics, Statistical Genetics, or a related scientific discipline.

The successful candidate will receive a competitive salary and benefits package along with the opportunity of working and collaborating with the best researchers and bioinformaticians in the UK.

As part of our recruitment process, all successful candidates are subject to a Standard Disclosure and Barring Service (DBS) check. We therefore require applicants to disclose any previous offences at point of application, as some unspent convictions may mean we are unable to proceed with your application due to the nature of our work in healthcare.

Genomics England operate a blended working model, as we know our people appreciate the flexibility. We expect most people to come into the office 2 times each month as a minimum. However, this will vary according to role and will be agreed with your team leader. For some people this is 1 day a quarter, for others it is several days a week. There is no expectation that staff will return to the office full time unless they want to. The exception would be some of our roles that would require you to be on site full time e.g., lab teams, reception team.

Our teams and squads have, and will continue to, reflect on what works best for them to work together successfully and have the freedom to design working patterns to suit, beyond the minimum. Our office locations at the moment are Cambridge and Farringdon (London) and in Autumn 2022 we are relocating our London office location to Canary Wharf. We will also be expanding our regional offices.

Looking ahead to our move to Canary Wharf, we will be designing our new space with blended working in mind, and with the flexibility to adapt to changing work patterns. During the pandemic we will be following government advice on working from home guidance.