Functional Cross-cutting GeCIP


More than 10 years have passed since the first high quality, complete version of the human genome was published. The most-­studied part is all that encodes  for proteins (known as the exome) and accounts for 2‐3% of the total human genetic code. The rest of the genome is much less understood.

Around half is composed of repetitive elements; one category of these, known as Endogenous Retroviruses (ERVs), is a remnant of ancient retroviral  infections of our ancient ancestors’ germ-cells, and make up around 5­‐8% of the human genome.

Our research explores potential health effects of human ERVs by combining bioinformatics and wet-lab approaches, with particular focus on trying to understand whether an association between particular ERV make up and incidence of disease can be found.

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