More than 10 years have passed since the first high quality, complete version of the human genome was published. The most-studied part is all that encodes for proteins (known as the exome) and accounts for 2‐3% of the total human genetic code. The rest of the genome is much less understood.
Around half is composed of repetitive elements; one category of these, known as Endogenous Retroviruses (ERVs), is a remnant of ancient retroviral infections of our ancient ancestors’ germ-cells, and make up around 5‐8% of the human genome.
Our research explores potential health effects of human ERVs by combining bioinformatics and wet-lab approaches, with particular focus on trying to understand whether an association between particular ERV make up and incidence of disease can be found.
- May 15, 2017
- Functional Cross-cutting GeCIP