Lung Cancer GeCIP Domain


Lung cancer is caused by uncontrolled cell growth in lung tissue. There are two main types – small-cell lung carcinoma, and non-small cell lung carcinoma. Worldwide, it is the most common cause of cancer-related death in men, and the second most-common in women. The vast majority of cases (85%) are caused by long term tobacco smoking. The remaining cases are due to air pollution, such as asbestos, second-hand smoke, or rare inherited types of lung cancer.

The lung cancer GeCIP domain will study the DNA of patient’s normal non-cancer tissue (germline) and tumour (somatic). They aim to better understand what changes occur in the DNA as the cancer spreads. They aim to find out if these DNA changes can help us to better characterise the tumour, and decide on more effective treatments to use.

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