Population Genomics GeCIP domain

Description

Project Summary 

Genome sequences from the 100,000 Genomes Project give an unprecedented genetic resource for the British population.  The population genomics GeCIP domain brings together leading UK researchers and collaborators from around the world. They will use the data to understand better how genetic variation has occurred in England. They will also generate information to facilitate other genetic analyses.

Aims

The researchers aim to improve understanding of the history of genetic mutation, recombination and genetic drift that has given rise to the genomes in the current population.  The results will inform them about the ancestry of samples, help fill in missing data for disease-oriented genetic studies, and improve the understanding of the recurrence risk for genetic disease caused by new mutations.  They will also combine geographic, epidemiological and genetic data to investigate the importance of these different factors in causing disease.

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