How we work

The Department of Health & Social Care set up Genomics England in 2013. Our aim is to deliver the 100,000 Genomes Project. Genomics England is a company owned by the Department of Health & Social Care. The Secretary of State is the only shareholder.

We are governed by a Board, led by an Executive Chairman.

Key Partners

We work with a range of partners to deliver the 100,000 Genomes Project:

100,000 Genomes Project

To identify and enrol participants for the 100,000 Genomes Project we have created NHS Genomic Medicine Centres (GMCs). Each centre includes several NHS Trusts and hospitals. GMCs recruit and consent patients. They then provide DNA samples and clinical information for analysis.

Illumina, a biotechnology company, have been commissioned to sequence the DNA of participants. They return the whole genome sequences to Genomics England. We have created a secure, monitored, infrastructure to store the genome sequences and clinical data. The data is analysed within this infrastructure and any important findings, like a diagnosis, are passed back to the patient’s doctor.

To help make sure that the project brings benefits for people who take part, we have created the Genomics England Clinical Interpretation Partnership (GeCIP). GeCIP brings together funders, researchers, NHS teams and trainees. They will analyse the data – to help ensure benefits for patients and an increased understanding of genomics. The data will also be used for medical and scientific research. This could be research into diagnosing, understanding or treating disease.

Find out more

To learn more about how we work you can read the 100,000 Genomes Project protocol. It has details of the development, delivery and operation of the project. It also sets out the patient and clinical benefit, scientific and transformational objectives, the implementation strategy and the ethical and governance frameworks.

Freedom of Information publication scheme

As a public authority we are obliged under the Freedom of Information Act to provide details of our routinely available information. We publish this information in accordance with the guidance as issued by the Information Commissioner’s Office. See more about the information we make routinely available and how it can be accessed.


“This International Standard specifies requirements for a quality management system that can be used by an organization involved in one or more stages of the life-cycle of a medical device, including design and development, production, storage and distribution, installation, servicing and final decommissioning and disposal of medical devices, and design and development, or provision of associated activities (e.g. technical support).” The Genomics England medical device is the Bioinformatics Pipeline 2.0 used in the clinical service.

Click here to download a copy

“This international standard specifies requirements for competency and quality that are particular to medical laboratories.” Though Genomics England is not a medical laboratory in the strict sense, we still have an obligation to be accredited to this standard as part of the genomic ecosystem comprising us, the sequence provider and the Genomic Laboratory Hubs that are classed as medical laboratories.

Click here to download a copy