Joining the 100,000 Genomes Project research community
Individuals can apply to become part of our research community – the Genomics England Clinical Interpretation Partnership (GeCIP).
GeCIP is organised into ‘domains’. These domains are groups of researchers, NHS clinical disease experts, NHS healthcare professionals and trainees. The domains align to the different diseases included in the 100,000 Genomes Project. There are also cross-cutting domains that carry out research across the whole of the project such as health economics, population genomics and machine learning. See the full list.
The aim of GeCIP is to carry out research and improve the understanding and practice of clinical genomics.
Are you a Participant interested in being involved in research?
Genomics England expects researchers working on the data from the 100,000 Genomes Project to work with Project Participants. To support this, we fund one patient and participant involvement (PPI) representative for each research domain. You can read the full role profile and responsibilities of a PPI representative here.
Proposing a new GeCIP domain
If you would like to propose a new GeCIP domain, please visit this page.
Become a member of an existing GeCIP domain
Please read the information below carefully, then use this form to apply to join an existing GeCIP domain:
Note that any member of staff at an NHS Genomic Medicine Centre that has helped to recruit patients can become a member relevant GeCIP domain if they request it using the application form above.
Students and post-docs are welcome to apply to join GeCIP through the student and post-doc application form. We request that students have a supervisor who is a member of the GeCIP domain they wish to join.
Membership of GeCIP is open to any individual, student or member of staff, who is affiliated with:
- UK academic research institutions (e.g. universities, research institutions etc.)
- NHS trusts or authorities
- UK and foreign charitable organisations directly related to the focus of the 100,000 Genomes Project
- Foreign universities and research institutions that carry out significant research activity
- UK and foreign governmental departments that carry out significant research activity (eg. MRC, NIH, PHE)
- Foreign healthcare organisations (private or public) that undertake significant research activity
Membership is not open to those who are self-employed or employed by:
- private UK healthcare institutions
- commercial companies.
Researchers from private healthcare institutions and commercial companies may be able to get involved in research using the 100,000 Genomes Project dataset through the Discovery Forum.
As a member of a GeCIP domain you will be given access to the 100,000 Genomes Project dataset. However, there are expectations of members of the GeCIP research community that go beyond data access and analysis. These include (please note, students are not expected to be able to meet all of these requirements):
- Contribution to the knowledge base for genome interpretation (for example via PanelApp)
- Active and effective collaboration within your GeCIP domain and with other GeCIP domains
- Expert assistance in genome interpretation to improve diagnostic yield for NHS Genomic Medicine Centres (GMCs)
- Contribution to training within your domain where needed
- Contribution to the ongoing management and administration of the GeCIP domain where requested
- Other activities in line with the provisions of the GeCIP Rules
Applicants should note that their proposed research plans may overlap with projects that are already part of the domain’s detailed research plan. Where such overlap exists, we would expect new GeCIP members to collaborate with those already undertaking the analysis.