Sample Handling Guidance

This Sample Handling Guidance covers rare disease and cancer sample requirements including blood, tumour and biopsy guidance for the 100,000 Genomes Project.

All links open as PDFs unless otherwise stated.

Latest Updates

Information in these documents will be included in the next version of the Sample Handling Guidance. In the meantime NHS GMCs can use this standalone guidance immediately.

Web Forms

This form should only be submitted if the form above has been sent and approval given

Using biobank consent

In the cancer programme, local biobank consent can be used for generic tissue, prior to participants being invited to join the 100,000 Genomes Project. Download the guidance.


View, download or print the current Sample Handling Guidance v3.1 Jan 2017.

NOTE: This web version (v3.1) contains some minor formatting and text changes.

Fullscreen Mode

Download: Sample Handling Guidance v3.1


For training in DNA extraction and sample processing, please visit the Genomics Education Programme website.

More information

Data submission guides

Includes guides to LabKey, Open Clinica, BuRST messaging, UAT and more.


Frequently asked questions on eligibility, recruitment, consent, samples, results and analysis.

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