Research Seminar: Pan-Cancer and Molecular Oncology

This month the research seminar will feature talks from members of the Pan-Cancer and Molecular Oncology community. 

Talk 1: OncoCommons: Federated Clinical Cancer Genomics Data, for research and care

About the talk: This presentation will introduce OncoCommons, a collaboration bringing together large cancer genomics datasets and working to make them more consistent and comparable for research. It will also help researchers understand where to access cancer genomics data and which datasets cover different cancer types.

Presenter: Joep de Ligt holds a PhD in bioinformatics and has extensive experience in human and infectious disease genomics. At Hartwig Medical Foundation, he works on making cancer treatment data-driven and making that data available for research. He also explores future developments in data federation and analysis, including pangenomics.
 

Talk 2: Global signatures of Ribonucleotide Excision Repair deficiency and its therapeutic vulnerabilities

About the talk: This presentation will explore how ribonucleotide excision repair (RER) deficiency creates distinctive patterns of DNA changes in cancer and how these patterns were used to develop the genomic classifier RERDetect. It will show how genomic sequencing can identify cancers with shared, potentially treatable biological features that may be missed by conventional gene-based diagnostics.

Presenter: Ping Jing is an MB/PhD student at the University of Cambridge. She completed her Bachelor of Arts in Cancer and Genetic Diseases with the Department of Pathology. She is currently in her final year of PhD in Genomics Medicine with Serena Nik-Zainal Lab. She is investigating the clinical applications and aetiology of mutational signatures found in DNA repair deficiencies.

About the research seminars:

The Genomics England Research Seminar series is a season of events held to demonstrate the best research from Genomics England and our partners. They started in October 2018, and are monthly, free-to-attend talks presented by Research Network members on the latest research being performed using data from the National Genomic Research Library.

The seminars will be held on the last Tuesday of each month at 2 to 3pm. These will be online sessions open to everyone and free to attend, we hope to have representation from across the Research Network and 100,000 Genomes Project participants as well as anyone else who would be interested in joining.

For updates on the seminars including announcements and speakers please follow the Genomics England twitter page. You can watch all previous Research Seminars on the Genomics England YouTube channel.

If you would like to present your research from the Genomics England Research Environment at one of these events please get in touch with the Research Management team at [email protected] and if you intend to publish on this research please include this so that we can publicise your paper on our Publications page.