Research Seminar: Omar Isaac Garcia Salinas and Luis Lopes

The Genomics England Research Seminar series is a season of events held to demonstrate the best research from Genomics England and our partners. They started in October 2018, and are monthly, free-to-attend talks presented by Research Network members on the latest research being performed using data from the National Genomic Research Library.

This month's seminar speakers from the Population Genomics community will be:

Omar Isaac Garcia Salinas - The impact of ancestral, environmental and genetic influences on germline de novo mutation rates and spectra

Isaac is interested in the genetic and environmental factors that influence complex phenotypes. He has experience functionally annotating SNPs associated with complex traits using in silico approaches. He recently completed his PhD at the Wellcome Sanger Institute under the supervision of Drs. Raheleh Rahbari and Hilary Martin. Part of his research focused on analysing the Genomics England trio cohort data to investigate the role of genetic ancestry, common variation, and smoking behaviour in shaping mutation rates and spectra in the human germline.

Luis Lopes - An analysis of mitochondrial variation in cardiomyopathy patients from the 100,000 genomes cohort: m.4300A>G as a cause of genetically elusive hypertrophic cardiomyopathy

Dr Lopes is a Clinical-Academic Consultant Cardiologist dedicated to Cardiomyopathies, Cardiogenetics, and Cardiac MRI at St. Bartholomew's Hospital and an Associate Professor at the Centre for Heart Muscle Disease, Institute of Cardiovascular Science, UCL. His main clinical focus is on Genetic Cardiomyopathies including Hypertrophic Cardiomyopathy, Dilated Cardiomyopathy, and Arrhythmogenic Cardiomyopathy, Metabolic Cardiomyopathies, Cardiac involvement in Neuromuscular conditions, and Mitochondrial Cardiomyopathy. Major research interests include the discovery of new genetic causes of cardiomyopathy and the use of advanced imaging in the construction of genotype-phenotype models and detection of early disease.

About the research seminars

The seminars will be held on the last Tuesday of each month at 2 to 3pm. These will be online sessions open to everyone and free to attend, we hope to have representation from across the Research Network, Discovery Forum and 100,000 Genomes Project participants as well as anyone else who would be interested in joining.

For updates on the seminars including announcements and speakers please follow the Genomics England twitter page. You can watch all previous Research Seminars on the Genomics England YouTube channel.

If you would like to present your research from the Genomics England Research Environment at one of these events please get in touch with the Research Management team at research-network@genomicsengland.co.uk and if you intend to publish on this research please include this so that we can publicise your paper on our Publications page.