PanelApp
The Genomics England PanelApp was created to enable virtual gene panels to be viewed and commented on by experts within the clinical and scientific community around the world.
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Improving diagnoses through expert consensus
Genomics England developed PanelApp to allow experts from around the world to share knowledge and insights on gene panels. Think of it like the Wikipedia of genes, with our dedicated team of curators checking every entry and a simple-yet-innovative 'traffic light' system indicating the level of evidence of a gene to cause a certain phenotype or disease.
Resources for NHS Genomic Medicine Service (GMS) users
View NHS GMS approved panelsA valuable resource for the scientific community
PanelApp provides the opportunity to encourage a consensus for which genes have enough evidence to be included on a diagnostic panel for a particular disease.
The aim is to use expertise and knowledge to establish a consensus final ‘green’ diagnostic grade gene panel for each disorder to aid clinical interpretation of genomes.
How PanelApp works
See the process for establishing panels below
How PanelApp is useful for you
Why be a PanelApp reviewer?
Share your expert knowledge
A community of experts with different backgrounds from around the world contribute
Improve diagnoses for patients
Help gain a consensus of which genes have a diagnostic-grade level of evidence
Capture your curation effort
Add your publications and put your curation efforts toward important outcomes
Download or query panels
PanelApp is open source, so you can gather information that you and others have contributed to
Get in touch
If you have any questions or suggestions, please email us.