The Lloyd sisters' story
Three sisters, Mary, Sandra, and Kerry Lloyd are early participants in the 100,000 Genomes Project.
Trying to find the cause of familial cancer
Three sisters, Mary, Sandra and Kerry Lloyd all developed breast cancer within 15 months of each other. They joined the 100,000 Genomes Project to understand more about their cancer – if it was inherited and what the risks to other family members might be.
The three sisters are not the only ones affected by cancer in their family. Their late mother had also been affected, as well as two other female relatives over three generations.
They had already undergone genetic testing for changes in the BRCA1 and BRCA2 genes – which can be a cause of breast cancer. But these tests didn’t find anything. The sisters donated a small amount of blood and had their genomes sequenced.
Bioinformaticians are now analysing the sequences to see if there are any changes in their 3.2 billion letters of DNA code that could be a cause of their cancer.
