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Academic research community (GECIP)

Academics, clinicians, and students worldwide can join our research community, the Genomics England Clinical Interpretations Partnership (GECIP, for short).

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Research projects by domain

Select from the domains and explore our active research projects.

Research projects for Glioma

Identifying novel treatments for Glioblastoma using Ex Vivo Screening

Glioma predisposition gene discovery

Identifying subtypes of Glioblastoma (GBM) patients via Network Approaches

Description of glioblastoma biomarkers in extracellular vesicles derived from patients’ blood

Quantifying subclonal evolutionary dynamics and intra-tumour heterogeneity

Using density of variants and mutational signatures to reconstruct chromatin accessibility maps

Measuring negative selection on essential genes and the immunopeptidome to assess immunoediting

Multi-omic profiling of glioma tumours

Elderly patients with glioblastoma

Determining the effects of adjuvant chemo/radiation therapy on glioma genomes

Identifying new molecular sub-types and pathways of glioma

Exploring the dynamics of extrachromosomal DNA drivers in gliomas

Genomic biomarkers of pseudoprogression

Predictive genomic biomarkers of transformation imaging phenotypes

Genomic and radiomic characteristics of glioma

Functional evaluation and interpretation of potential driver variants in glioma and follow-up analyses in additional data sets and model systems

Assessing the contribution of inherited variation to glioma risk

Genomic characterisation of unusual glioma cases

Integrating genomics and glioma clinical trials

Identification and characterisation of mitochondrial and viral genomes in glioma

Glioma research plan

Full details of the research proposed by this domain

Glioma detailed research plan

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